Categoría: Heart Disease
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The Role of Adult Stem Cells in Angioplasty
The National Institute of Health has granted the Creighton School of Medicine $3.3 million dollars to study repairing damaged coronary arteries with adult stem cells. Such damage can occur when patients undergo coronary artery angioplasty and stenting. A serious problem that occurs is the re-narrowing (restenosis) of coronary arteries after stent placement. Stents are used…
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Medistem and Licensee ERCell Receive Russian Regulatory Approval for the RECOVER-ERC Trial
The clinical trial, Non-Revascularizable IschEmic Cardiomyopathy treated with Retrograde COronary Sinus Venous DElivery of Cell TheRapy (RECOVER-ERC), is being led by Principle Investigator Dr. Leo Bockeria, Chairman of the Backulev Center http://www.bakulev.ru/en/about/director/. The Backulev Center is Russia’s premier institute for cardiovascular surgery and cardiology. Every year the Backulev Center performs approximately 30,000 diagnostic and treatment…
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PRECISE: Adipose-derived stem cells show utility as therapy
Cardiology Today PRECISE is The Randomized Clinical Trial of Adipose-Derived Stem Cells in Treatment of Non Revascularizable Ischemic Myocardium, a double blind, placebo-controlled trial involving 27 patients with chronic ischemic heart disease with HF, angina or both, who were not eligible for percutaneous or surgical revascularization. The patients in the study underwent a liposuction to…
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Scientists look to stem cells to mend broken hearts
Cardiac medicine has traditionally been associated with innovative procedures that sometimes where considered heretical to the present day dogma. For example, the first heart transplant, the use of the balloon catheter, the introduction of thrombolytics, all met substantial resistance from the “establishment” in their time. It appears that the next revolution in cardiac medicine is…
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Stem Cell Institute in Panama Collaborates on New Method of Treating Diabetes-Associated Heart Disease
Zhang et al. Journal of Translational Medicine Diabetes is associated with numerous “secondary complications” including premature heart disease, renal failure, critical limb ischemia (an advanced form of peripheral artery disease) and diabetic retinopathy. One of the common features of these secondary complications is that they are all associated with low levels of circulating endothelial progenitor…
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Stem cell therapy benefits patients with chronic heart failure—study
(Neharika Sabharwal) After a heart attack the myocardium (heart muscle) undergoes a period of damage during which cells of the body attempt to heal the injured tissue. This occurs through stem cells found in the heart itself, called cardiac specific stem cells (CSC) as well as bone marrow stem cells which seem to exit the…
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Success Stems From Adult Cells
The use of adult stem cells for conditions besides bone marrow transplant is most prevalent in the area of heart failure. Since the original study of Strauer et al in 2001 in which a 46-year old patient was administered bone marrow stem cells after a heart attack and experienced a profound improvement in cardiac function,…
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Stem Cell Institute Panama Clinic Case Report of Successful Treatment of Heart Failure Patient Published
Adult stem cell therapy is currently in numerous clinical trials in the United States and Internationally. A sample of ongoing trials can be seen at www.clinicaltrials.gov if you search for the words "stem cell". In clinical trials the objective is to determine safety (in Phase I), efficacy in an unblinded manner (Phase II) and efficacy…
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Stem Cells Don’t have to be Alive to Be Beneficial
The use of stem cells in patients who have poor circulation is well-known. In fact, the first use of stem cells for conditions other than blood disorders was in patients who were undergoing bypass surgery. Usually patients undergo bypass because of advanced atherosclerosis that is inhibiting the flow of blood to the heart muscle. Despite…
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Magnetic Attraction of Stem Cells to Injured Heart Creates Potent Treatment
The intracoronary administration of bone marrow stem cells in patients who have suffered a heart attack has been demonstrated to cause beneficial effects in double blind studies, as discussed in this video http://www.youtube.com/watch?v=flv0RmzPyLU. Intracoronary administration has potential side effects since a balloon needs to be expanded in the area where the heart attack occurred, which…