Etiqueta: immune
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Why should mesenchymal stem cells (MSCs) cure autoimmune diseases?
Uccelli A, Prockop DJ. Curr Opin Immunol. 2010 Dec;22(6):768-74. Epub As many readers of Cellmedicine News most likely realize, the concept of stem cell therapy is still relatively controversial. Despite the fact that clinical trials have demonstrated therapeutic signals that various stem cells are useful in treatment of diseases ranging from multiple sclerosis, to type…
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Beike Biotechnology Reports on 114 Patients Treated with Novel Cord Blood Stem Cell Protocol
New Approach Opens Door to Expanded Uses of Cord Blood Stem Cells Beike Biotechnology Press Release Beiki Biotechnology and Medistem Inc (MEDS.PK) report positive safety data in 114 patients with neurological conditions treated using Beiki’s proprietary cord blood stem cell transplantation protocol. In the peer-reviewed paper “Safety evaluation of allogeneic umbilical cord blood mononuclear cell…
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Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: a pilot clinical study.
Liang et al. Ann Rheum Dis. 2010 Aug;69(8):1423-9. Mesenchymal stem cells are unique in that on the one hand they are capable of differentiating into a variety of tissues, but on the other hand they also are potently anti-inflammatory and immune modulatory. Evidence of immune modulation comes from studies that show mesenchymal stem cells: a)…
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Pluripotent stem cell-derived natural killer cells for cancer therapy.
Knorr et al. Transl Res. 2010 Sep;156(3):147-154. Epub Immune therapy of cancer is an exciting prospect given the possibility of treating cancer without the side effects associated with conventional treatments such as chemotherapy or radiotherapy. Additionally, the use of the immune system to target tumors offers the possibility of eradicating micrometastasis, which often cannot be…
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Ahmedabad-based institutes get patent to use stem cells in kidney transplant
According to an article IndianExpress.com, an international patent has been issued to the G R Doshi K M Mehta Institute of Kidney Diseases and Research Centre (IKDRC) and Dr HL Trivedi Institute of Transplantation Sciences (ITS) from Ahmedabad, Indian for utilization of stem cells in treatment of patients having undergone kidney transplantation. Given that we…
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Stem Cells for HIV?
HIV infection causes its devastating effects on patients by destruction of the CD4 T helper cell and macrophage component of the immune system. Entry of the virus into these cells occurs via binding to the molecules CD4 and CCR5. Interestingly a group of patients who appear to be resistant to HIV infection have a mutation…