Etiqueta: mesenchymal
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Why should mesenchymal stem cells (MSCs) cure autoimmune diseases?
Uccelli A, Prockop DJ. Curr Opin Immunol. 2010 Dec;22(6):768-74. Epub As many readers of Cellmedicine News most likely realize, the concept of stem cell therapy is still relatively controversial. Despite the fact that clinical trials have demonstrated therapeutic signals that various stem cells are useful in treatment of diseases ranging from multiple sclerosis, to type…
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What Works Better: Stem Cell Mobilization or Stem Cell Administration for Brain Injury
Bakhtiary et al. Iran Biomed J. 2010 Oct;14(4):142-9. Bone marrow mobilization is used as part of hematopoietic stem cell transplantation in order to collect donor bone marrow stem cells without having to puncture the bone. The process of mobilization is induced by administration of the drug G-CSF, which is approved by the FDA. One interesting…
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Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: a pilot clinical study.
Liang et al. Ann Rheum Dis. 2010 Aug;69(8):1423-9. Mesenchymal stem cells are unique in that on the one hand they are capable of differentiating into a variety of tissues, but on the other hand they also are potently anti-inflammatory and immune modulatory. Evidence of immune modulation comes from studies that show mesenchymal stem cells: a)…
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Stem Cells for Spinal Cord Injury
The use of mesenchymal stem cells for a variety have diseases has been published. This includes conditions such as heart failure, liver failure, stroke, and lupus. One of the attractive features of mesenchymal stem cells is that they can differentiate into numerous tissues while at the same time exerting anti-inflammatory activities. In the situation of…