Etiqueta: research
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Scientists look to stem cells to mend broken hearts
Cardiac medicine has traditionally been associated with innovative procedures that sometimes where considered heretical to the present day dogma. For example, the first heart transplant, the use of the balloon catheter, the introduction of thrombolytics, all met substantial resistance from the “establishment” in their time. It appears that the next revolution in cardiac medicine is…
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Nine Patients with Crohn’s Disease Treated by Intravenous Administration of Mesenchymal Stem Cells
Marjolijn et al. Gut 59:1662 Mesenchymal stem cells are known to be suppressive to immune cells such as T cells, dendritic cells, and natural killer cells. Studies have demonstrated that patients suffering from the immune disease graft versus host enter remission after administration of donor or third party mesenchymal stem cells. One of the manifestations…
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Male-Pattern Baldness Found Rooted in Stem Cells
Amanda Chan, MyHealthNewsDaily Staff Writer A new discovery regarding the presence of stem cells in males with androgenetic alopecia (male-pattern baldness) has led to hope that the disease may be treatable. It was previously believed that people who suffered from baldness also had a depleted number of hair follicle stem cells, meaning that new hair…
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Study Shows Patient’s Own Stem Cells Help Stroke Recovery: 16 Treated Patients Improve in Comparison to 36 Controls
Lee et al Stem Cells 28:1099 Stroke is caused by blocked circulation to parts of the brain usually as a result of a blood clot. Outcomes of stroke are generally proportional to the length of time the circulation was blocked and to the amount of brain tissue injury and death. Although the introduction of “clot…
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Differences between Stem Cells from the Placenta and Bone Marrow
Fazekasova et al. Mesenchymal stem cells were historically isolated from the bone marrow as an adherent stem cell population capable of “orthodox” differentiation, meaning that they have ability to become bone, cartilage, and fat. Further research revealed that these cells are also capable of “non-orthodox” differentiation, that is, becoming neurons, hepatocytes, insulin producing cells, and…
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Men with Type 1 diabetes eventually may have a way to grow their own pancreas transplants
Thomas H. Maugh II, Los Angeles Times Researchers from Georgetown University Medical Center in Washington DC reported today at the Annual Meeting of the American Society of Cell Biology that sperm contains stem cells capable of becoming beta cells. The beta cells are the insulin producing cells of the pancreas which are damaged/destroyed in patients…
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Mechanisms of a New Stem Cell Mobilizer
Jarcome-Galarza et al. J Bone Miner Res. It is known that the bone marrow contains three main types of stem cells: a) hematopoietic stem cells, which make blood; b) endothelial progenitor cells, which maintain healthy blood vessels; and c) mesenchymal stem cells, which repair a variety of tissues and are capable of producing high amounts…
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Enhancing Efficacy of Bone Marrow Transplant
Huang et al. Blood. [Epub ahead of print] Bone marrow transplantation has cured many patients of hematological diseases such as leukemias and lymphomas. Additionally, bone marrow transplantation is becoming used more and more in treatment of autoimmune diseases such as type 1 diabetes and multiple sclerosis. Unfortunately, there are still numerous limitations to this procedure.…
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Resveratrol Suppresses Cancer Stem Cells
Pandey et al. Breast Cancer Res Treat. Resveratrol is a compound found in grapes, red wine, purple grape juice, peanuts, and berries that has been associated with many health benefits, particularly reduction in heart disease. Some studies have demonstrated that resveratrol increases life span when administered at high concentrations. One area of controversy has been…
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Increasing Efficacy of Stem Cell Therapy for Spinal Cord Injury
Jin et al. Spine (Phila Pa 1976). Clinical trials of stem cells for treatment of spinal cord injury are currently being conducted in the United States and abroad. For example, the Covington Louisiana company TCA Cellular Therapy LLC is recruiting 10 patients with spinal cord injury to receive intrathecal infusion (lumbar puncture) of autologous, ex…