Etiqueta: stem cells
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A Fall for Stem Cells Injunction Halting Stem Cell Research Funds May Have Far-Reaching Consequences
(STEPHEN BROZAK and LARRY JINDRA, M.D. ABC News) There is some anticipation that this fall will be an important season for the debate on embryonic stem cell research. On Aug 30, 2010 a Washington, DC district judge (Lamberth), issued a temporary injunction halting all federal funding for basic research into embryonic stem cell technology. The…
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Immunomodulation of Delayed-Type Hypersensitivity Responses by Mesenchymal Stem Cells Is Associated with Bystander T Cell Apoptosis in the Draining Lymph Node.
(Lim et al. J Immunol) Immune responses are quantified in many ways. Typically one thinks about immunity as the ability of an organism to overcome infection with another organism. However this test is impossible to perform in a reproducible, quantitative, and ethical way in humans. An alternative test was developed by immunologists called delayed type…
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Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: a pilot clinical study.
Liang et al. Ann Rheum Dis. 2010 Aug;69(8):1423-9. Mesenchymal stem cells are unique in that on the one hand they are capable of differentiating into a variety of tissues, but on the other hand they also are potently anti-inflammatory and immune modulatory. Evidence of immune modulation comes from studies that show mesenchymal stem cells: a)…
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Pluripotent stem cell-derived natural killer cells for cancer therapy.
Knorr et al. Transl Res. 2010 Sep;156(3):147-154. Epub Immune therapy of cancer is an exciting prospect given the possibility of treating cancer without the side effects associated with conventional treatments such as chemotherapy or radiotherapy. Additionally, the use of the immune system to target tumors offers the possibility of eradicating micrometastasis, which often cannot be…
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Stem Cells for Spinal Cord Injury
The use of mesenchymal stem cells for a variety have diseases has been published. This includes conditions such as heart failure, liver failure, stroke, and lupus. One of the attractive features of mesenchymal stem cells is that they can differentiate into numerous tissues while at the same time exerting anti-inflammatory activities. In the situation of…
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Eradication of brain tumor stem cells with an oncolytic adenovirus.
Jiang et al. Discov Med. 2010 Jul;10(50):24-8. Philosophically, tumor cells have an advantage to humans in the “War on Cancer”. That is, the tumors have the ability to rapidly mutate, so that when drugs are given to fight the tumor, the tumor can “mutate around” the drug and become resistant. This occurs in several ways:…
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Arthritis Patient Successfully Treated With Fat Stem Cells Tells His Story
This procedure has been used successfully to treat thousands of animals suffering from arthritis in the United States (www.vet-stem.com). Recently Dr. Paz published a paper describing scientific mechanisms of this treatment in collaboration with scientists from the University of California San Diego, University of Western Ontario, and Medistem Inc (Ichim et al. Autologous stromal vascular…
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Medistem Reports Rheumatoid Arthritis Patient Success Using Adult Stem Cell Protocol
SAN DIEGO, CA – (Marketwire – June 21, 2010) – Medistem Inc. Medistem Inc. together with the Stem Cell Institute reported today publication in the peer reviewed journal Cellular Immunology its paper titled «Autologous stromal vascular fraction cells: A tool for facilitating tolerance in rheumatic disease,» which describes the first use of a patient’s own…
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Pluristem’s Off-The-Shelf Placenta-Derived Cell Therapies
Pluristem announced that its "off the shelf" placental stem cells will be the focus of upcoming talking at investor and medical conferences. The company Pluristem is currently in Phase I trials assessing its unique bio-reactor expanded placental stem cells for the treatment of critical limb ischemia. In contrast to other therapies that use the patient’s…
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Identification of Peptides Which Show Potential To Generate Cancer Stem Cell Specific Immune Responses
The use of the immune system to target cancer has been a therapeutic goal for over a century. The advantage of immunotherapy is the possibility of targeting cancer throughout the body in a non-toxic manner, thus allowing destruction of metastasis, and induction of immunological memory to protect from relapse. Unfortunately with exception of the recent…