Categoría: Stem Cell Research
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Differences between Stem Cells from the Placenta and Bone Marrow
Fazekasova et al. Mesenchymal stem cells were historically isolated from the bone marrow as an adherent stem cell population capable of “orthodox” differentiation, meaning that they have ability to become bone, cartilage, and fat. Further research revealed that these cells are also capable of “non-orthodox” differentiation, that is, becoming neurons, hepatocytes, insulin producing cells, and…
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Men with Type 1 diabetes eventually may have a way to grow their own pancreas transplants
Thomas H. Maugh II, Los Angeles Times Researchers from Georgetown University Medical Center in Washington DC reported today at the Annual Meeting of the American Society of Cell Biology that sperm contains stem cells capable of becoming beta cells. The beta cells are the insulin producing cells of the pancreas which are damaged/destroyed in patients…
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Mechanisms of a New Stem Cell Mobilizer
Jarcome-Galarza et al. J Bone Miner Res. It is known that the bone marrow contains three main types of stem cells: a) hematopoietic stem cells, which make blood; b) endothelial progenitor cells, which maintain healthy blood vessels; and c) mesenchymal stem cells, which repair a variety of tissues and are capable of producing high amounts…
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Stem cells in the Brains of Crayfish
Ayub et al. Dev Neurobiol. Stem cells have been found in various organs to participate in repair after injury. For example, after a heart attack, cardiac specific stem cells that reside in the atrium are known to proliferate and cause repair of damage. In the brain stem cells participate in a variety of processes, for…
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Enhancing Efficacy of Bone Marrow Transplant
Huang et al. Blood. [Epub ahead of print] Bone marrow transplantation has cured many patients of hematological diseases such as leukemias and lymphomas. Additionally, bone marrow transplantation is becoming used more and more in treatment of autoimmune diseases such as type 1 diabetes and multiple sclerosis. Unfortunately, there are still numerous limitations to this procedure.…
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Resveratrol Suppresses Cancer Stem Cells
Pandey et al. Breast Cancer Res Treat. Resveratrol is a compound found in grapes, red wine, purple grape juice, peanuts, and berries that has been associated with many health benefits, particularly reduction in heart disease. Some studies have demonstrated that resveratrol increases life span when administered at high concentrations. One area of controversy has been…
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Increasing Efficacy of Stem Cell Therapy for Spinal Cord Injury
Jin et al. Spine (Phila Pa 1976). Clinical trials of stem cells for treatment of spinal cord injury are currently being conducted in the United States and abroad. For example, the Covington Louisiana company TCA Cellular Therapy LLC is recruiting 10 patients with spinal cord injury to receive intrathecal infusion (lumbar puncture) of autologous, ex…
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Time to end stem cell institute CIRM
Wesley J. Smith , San Francisco Chronicle The California Institute for Regenerative Medicine (CIRM) was created in 2004 as a result of the California Proposition 71, which called for a new bond issue to generate 3 billion dollars in order to support stem cell research in the State. In part, the institute was created as…
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Stem Cell Institute in Panama Collaborates on New Method of Treating Diabetes-Associated Heart Disease
Zhang et al. Journal of Translational Medicine Diabetes is associated with numerous “secondary complications” including premature heart disease, renal failure, critical limb ischemia (an advanced form of peripheral artery disease) and diabetic retinopathy. One of the common features of these secondary complications is that they are all associated with low levels of circulating endothelial progenitor…
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How Inflammation Suppresses Stem Cell Function
Wang et al. PLoS One;5(12):e14206. Low grade inflammation is well known to correlate with development of numerous disease conditions such as heart failure, kidney failure, and diabetes. It is generally accepted that oxidative stress caused by inflammation is one of the means by which disease evolution occurs. Inflammatory conditions usually generate oxygen free radicals that…