Categoría: Stem Cell Research
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Membrane Voltage Changes Control Timing of Stem Cell Differentiation
Researchers at Tufts University have discovered that changes in voltage which naturally occur across adult human stem cell membranes act as a powerful control mechanism which determines the timing of stem cell differentiation. Led by Dr. Michael Levin, the scientists have shed new light on the role that electrophysiology plays in the differentiation and proliferation…
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Why should mesenchymal stem cells (MSCs) cure autoimmune diseases?
Uccelli A, Prockop DJ. Curr Opin Immunol. 2010 Dec;22(6):768-74. Epub As many readers of Cellmedicine News most likely realize, the concept of stem cell therapy is still relatively controversial. Despite the fact that clinical trials have demonstrated therapeutic signals that various stem cells are useful in treatment of diseases ranging from multiple sclerosis, to type…
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What Works Better: Stem Cell Mobilization or Stem Cell Administration for Brain Injury
Bakhtiary et al. Iran Biomed J. 2010 Oct;14(4):142-9. Bone marrow mobilization is used as part of hematopoietic stem cell transplantation in order to collect donor bone marrow stem cells without having to puncture the bone. The process of mobilization is induced by administration of the drug G-CSF, which is approved by the FDA. One interesting…
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Beike Biotechnology Reports on 114 Patients Treated with Novel Cord Blood Stem Cell Protocol
New Approach Opens Door to Expanded Uses of Cord Blood Stem Cells Beike Biotechnology Press Release Beiki Biotechnology and Medistem Inc (MEDS.PK) report positive safety data in 114 patients with neurological conditions treated using Beiki’s proprietary cord blood stem cell transplantation protocol. In the peer-reviewed paper “Safety evaluation of allogeneic umbilical cord blood mononuclear cell…
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Scientists identify and isolate adult mammary stem cells in mice
(Times of India) It is well-known that stem cells exist in adult tissues. The most commonly known stem cell, the bone marrow stem cell, plays the physiological role of generating billions of blood cells per hour while being capable of making copies of itself. Subsequent to the discovery of the bone marrow stem cell in…
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Stem cell therapy benefits patients with chronic heart failure—study
(Neharika Sabharwal) After a heart attack the myocardium (heart muscle) undergoes a period of damage during which cells of the body attempt to heal the injured tissue. This occurs through stem cells found in the heart itself, called cardiac specific stem cells (CSC) as well as bone marrow stem cells which seem to exit the…
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Pluristem to take part in EU stem cell study
(Shiri Habib-Valdhorn, Globes [online], Israel business news) Broadly speaking there are two types of adult stem cell therapies: Those that involve the use of the patient’s own stem cells, called autologous, and those that involve use of another patient’s cells, called allogeneic. There are pros and cons to both approaches. In the autologous approach the…
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A Fall for Stem Cells Injunction Halting Stem Cell Research Funds May Have Far-Reaching Consequences
(STEPHEN BROZAK and LARRY JINDRA, M.D. ABC News) There is some anticipation that this fall will be an important season for the debate on embryonic stem cell research. On Aug 30, 2010 a Washington, DC district judge (Lamberth), issued a temporary injunction halting all federal funding for basic research into embryonic stem cell technology. The…
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Immunomodulation of Delayed-Type Hypersensitivity Responses by Mesenchymal Stem Cells Is Associated with Bystander T Cell Apoptosis in the Draining Lymph Node.
(Lim et al. J Immunol) Immune responses are quantified in many ways. Typically one thinks about immunity as the ability of an organism to overcome infection with another organism. However this test is impossible to perform in a reproducible, quantitative, and ethical way in humans. An alternative test was developed by immunologists called delayed type…
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Platelet-Rich Plasma Releasate Promotes Differentiation of Tendon Stem Cells Into Active Tenocytes.
(Zhang et al. Am J Sports Med. ) Platelet rich plasma (PRP) contains products of activated platelets which include numerous growth factors such as fibroblast growth factor, hepatocyte growth factor, insulin like growth factor, etc. Conventionally, PRP is used to promote various healing processes. In the area of sports medicine PRP has been used for…